Scientific Reports：鋁在腦中的毒性
【30秒重點】
- 想了解鋁的影響，可以留意疫苗說明書上的鋁含量。
- Scientific Reports研究測了20位沒有神經退化疾病捐贈者的腦組織鋁含量。
- 研究拿來和阿茲海默症、多發性硬化症和自閉症病人的腦組織比較。
- 作者提醒讀者聯想到疫苗中的鋁；研究本身沒有測疫苗。
2022/03/17
值得一讀。想想疫苗中的鋁，之前寫過多次。
Abstract
A burgeoning number of studies are demonstrating aluminium in human brain tissue. While research has both quantified and imaged aluminium in human brain tissue in neurodegenerative and neurodevelopmental disease there are few similar data for brain tissue from non-neurologically impaired donors. We have used microwave assisted acid digestion and transversely heated graphite furnace atomic absorption spectrometry to measure aluminium in twenty brains from donors without recognisable neurodegenerative disease. The aluminium content of 191 tissue samples was invariably low with over 80% of tissues having an aluminium content below 1.0 μg/g dry weight of tissue. The data for these control tissues were compared with data (measured using identical procedures) for sporadic Alzheimer’s disease, familial Alzheimer’s disease, autism spectrum disorder and multiple sclerosis. Detailed statistical analyses showed that aluminium was significantly increased in each of these disease groups compared to control tissues. We have confirmed previous conclusions that the aluminium content of brain tissue in Alzheimer’s disease, autism spectrum disorder and multiple sclerosis is significantly elevated. Further research is required to understand the role played by high levels of aluminium in the aetiology of human neurodegenerative and neurodevelopmental disease.
谷歌翻譯：
越來越多的研究表明人類腦組織中存在鋁。雖然研究已經對神經退行性疾病和神經發育疾病中人腦組織中的鋁進行了量化和成像，但對於來自非神經受損供體的腦組織的類似數據卻很少。我們使用微波輔助酸消解和橫向加熱石墨爐原子吸收光譜法來測量來自沒有可識別的神經退行性疾病的 20 個供體大腦中的鋁。 191 個組織樣本的鋁含量始終較低，超過 80% 的組織的鋁含量低於 1.0 μg/g 組織乾重。這些對照組織的數據與散發性阿爾茨海默病、家族性阿爾茨海默病、自閉症譜系障礙和多發性硬化症的數據（使用相同程序測量）進行了比較。詳細的統計分析表明，與對照組織相比，這些疾病組中的每一個中的鋁都顯著增加。我們已經證實了之前的結論，即阿爾茨海默病、自閉症譜系障礙和多發性硬化症的腦組織中鋁含量顯著升高。需要進一步的研究來了解高水平鋁在人類神經退行性疾病和神經發育疾病的病因學中所起的作用。
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